Is This the Key to Reversing Aging?

I've mentioned this before in another article (see here ).  Age is something that can be treated with a better understanding of the human body and great treatment technologies.

In essence, research shows that aging is a deterioration of human cells eventually leading to a critical part of the body shutting down.  The cells of the heart, brain, lungs or other tissues just get too badly damaged that the tissues and systems just can't function anymore.  And then we pass away.

Organizations like Human Longevity, inc. and the SENS Research Foundation in the US are focusing their entire resources in finding treatments for one or several of the 7 biological causes of aging:

1. Cell loss / atrophy
2. Death-resistant cells
3. Nuclear mutations and epimutations
4. mtDNA mutations
5. Protein crosslinks
6. Junk accumulated inside cells
7. Junk accumulated outside cells

I mentioned earlier this year there was a treatment that was going to human trials sometime in 2017 that would help with the some causes of aging (nuclear mutations and mtDNA mutations). 

Scientists have also made some headway in correcting another cellular problem that occurs with age:  cell loss without any replacements.  You've probably heard that cells divide only a certain number of times in our body's life (those that aren't stem cells that is, which is the majority of the cells in our body).  Scientists think that this is because of a part of our chromosomes, the tail ends, or telomeres, which shorten with time, eventually making cellular division impossible.  Thus cells that die don't get replaced, leading to a whole lot of aging-related issues.

Researchers at the Houston Methodist Research Institute did some research recently with patients affected by progeria.  Progeria is a genetic disease where babies are born with accelerated aging, to such an extent that they look like 80 year olds by the age of 12 or so, and typically die of age-related issues by the age of 15.   The researchers treated patients with RNA molecules that encode RNA telomerase forcing the progeria patients to produce RNA telomerase in their own cells.  RNA telomerase then works on elongating the telomeres in each cell.  

The results were encouraging because most patients' cells started dividing normally again, helping with the regeneration of tissues and also reducing the amount of inflammatory proteins the cells produce (toxic in high levels).  In essence, the laboratory was able to reverse part of the person's aging processes by making the cells act as if they were younger.  

Other laboratories are working on fixing the gene that causes this problem in the first place, possibly using the CRISPR protein complex.  That would be best.  However, the work of the Houston laboratory does relieve the disease's symptoms in patients and have given us a tool that could be used on anyone to help counter and reverse some of the processes related to aging.

That's great stuff but to me the most impressive discovery around aging came from the researchers at Albert Einstein College of Medicine, who have found that adult stem cells located specifically in the hypothalamus may be responsible to activate multiple mechanisms of aging altogether.

I talk about this particular discovery further and it's potential impacts in the video below:

Now, we know that these hypothalamus stem cells are responsible for neurogenesis (the generation of new neurons) and we know from measurements that the population of these specific stem cells decreases as an animal ages (including humans).

We also know from the research that these stem cells produce what we call micro RNA (miRNA) that seem to have no other function except for regulating the expression of various genes in the body.  Contrary to most RNA that never leave the cell where they are produced, these flow into the bloodstream and enter other cells in the body.  So as the population of these stem cells decreases with time, less miRNA is produced ergo fewer genes that are regulated are activated or deactivated when needed.

According to my information we know little about which genes the hypothalamus-produced miRNA regulate but it they seem to be important in keeping tissues young because when the Albert Einstein College of Medicine researchers injected miRNA into the brains of old mice or mice that had their hypothalamus stem cells destroyed, many aging-related symptoms were halted or even reversed.  The results were the same if the researchers injected stem cells into the mice's hypothalamus region.

We can only speculate that if we can keep the stem cell population of our hypothalamus at a high level, many aging-related issues would be averted.  So far, I don't think we know why these cells die off over time, because stem cells typically just keep reproducing themselves infinitely and do not age like differentiated tissue cells.

A researcher in longevity that I know, Dr. Aubrey de Grey, from the SENS Research Foundation, when asked about the potential of this particular discovery, told me that for now, the impact of it all isn't that significant, but I have a sneaky suspicion that many of the age-related issues are related to one another through these hypothalamus adult stem cells.

Time and more research will tell...

 

Revolution Science - Gene Editing, Major Cures & Eugenics

Today, I was reading up on genetic advancements and reread an article that came across my desk about a week ago.  I thought to myself:  I really, really need to get this out a bit more because the consequences of this research being "out" are astounding.

True enough, since this came out about 3 years ago from the labs (once again, very well documented, peer-reviewed science, well supported), a great many startups have picked up on it to create applications in the real world and many Venture Capital companies have invested huge sums to get it all going.

Dr.  Jennifer Doudna, Berkeley University, California

In the following Youtube video I talk a bit more about this and integrated into my video is the TED talk video from the head researched herself that published the paper a few years back.  She describes the technique and its potential applications better than I ever could.  Check it out:

Bottom line, this is once more a revolutionary piece of science that, in just a few years, will change our world.

Why?

We can soon say goodbye to potentially ALL genetic diseases. 
For example:

• Cystic Fibrosis
• Tay-Sachs disease
• Some cancers
• Sickle Cell Disease
• Huntington's Disease
• Many more

We can also say hello to  possibilities in:

• Genetic human enhancements
• Designer babies
• Designer pets and other animals
• Cures for retroviral and persistent genetic viral infiltration diseases such as:
• AIDS
• Herpesvirus
• Proviruses

This is very exciting because we can get, as a human species, get more ownership over our own physical bodies, customizing it the way we want and feeling more in control of what it does (eradication of some diseases). 

Others would likely say that this is terrible news since governments and corporations would also be able and likely will use this technology to create better soldiers and biological weapons.  Using this tech, it would be pretty simple to create a bio weapon that would target a certain population for example and make them extremely sick (disable) on a genetic level.

I'm of the opinion that science must advance and we have to lobby, and be active in our desire as a society to see through ONLY the positive applications of great technologies.  Science is not evil... only people can be evil (people hungry for power.

For those of you who believe this can be "canned"... its unlikely at this point.  Way too much money has been spent from investors to take this new research down into oblivion, just too much money to be made.  But this time into long duration cures.  Not only that, but with the CRISPR technology, we can also heal the gametogenesis cells of both genders so that they cannot transmit whatever genetic defect they have to their children.  Cool huh?

One of many startups using CRISPR to attempt genetic cures and other genetic modifications

 

One of the biotechnology companies in the race to make things happen, Editas Medicine, hopes to do human testing on a specific genetic disease by 2017, a genetic eye disorder that renders people carrying the erroneous gene blind, called Leber congenital amaurosis, cure it and report findings.  If successful with this one disease, they hope that the FDA will approve more testing for other diseases and release them to offer a cure for this disease to all affected desiring treatment.

And you know what?  The technique is super simple and inexpensive they say.  How that translates into $$$ and cents, we'll soon see but sounds good to me!

For the biochemistry and biology fans out there, here is a picture of the process involving CRISPR and the Cas9 protein at work in cutting the bad gene and duplicating a healthy DNA copy below.

Cas9 at work during the CRISPR process of editing a gene

 

So keep watch for more developments on this in a couple years where we'll start seeing firms, hospitals and not-for-profit organizations offering treatment for all sorts of debilitating diseases as well as all sorts of beneficial designer genetic modifications to the population... for a cost... :) .

 

Keep the revolution going, using great science! 

 

Support this sort of excellent research everywhere and we can create our own paradise of peace, harmony and health for all soon enough.

 

Keshe Technologies - Part 2 - Scam Detection Tips

Since last week there were several comments about the Keshe Technology plasma energy generator post, I decided to do a Part 2 specifically to help people discern what is "scammy" and what isn't.  

Most of the comments here and on Youtube were about people trying to figure out if this is real or not and I've had several questions from people here and there about other opportunities for change out there and whether or not they are "real".

Here are the tips in rough format but, as always, for more details and explanations, watch the video below:

Just a quick note to let you know that we haven't received the generators from the Keshe Foundation yet so before I post any result and further analysis on the validation or feasibility of Free Energy using this technology (as well as the reverse engineering, blueprinting etc....), me and my science and engineering friends will want to receive and do a battery of tests on those babies.  We'll also dismantle them to make sure we understand the guts of it, and ferret out any misleading energy sources that may be hidden etc...

I do a summary of the Keshe Technology evaluation after we go through the Scam Detection Tips below:

1.   Validation - 3rd party checks and balances: 

First, check if the product is in large physical retail stores somewhere like North America, Europe or advanced Asian countries where regulatory bodies check things out.  Large retail stores depend on regulatory bodies to validate new products in order to avoid lawsuits and other problems.  If the product has passed this test, it means its not harmful or scammy.  This does NOT guarantee the product will provide any significant benefit to you or your family, just that it is generally "safe" and a real product.  Online stores don't apply here.  Needs to be real shelves of a well known reputable store (or chain).

If you can't find the product on shelves, then you look for validation from experts.  This means 3rd party research firms or other unrelated well organized people that did proper testing.  By proper testing, I mean double blind study or reverse engineering.  Double blind means there is a first sample group of people given the product and told what it does and the other group that receives a placebo product and told the exact same thing.  If the first group with the actual product see a difference, then the product is necessary real since that's the only difference between the groups.  The placebo group may see results but due to their own imagination....  however the "real deal" will be noticeably different.  In the case of hard engineering, like M. Keshe's reactor, 3rd party testing by professional engineers is needed like what we'll be attempting directly after we receive the devices.

2.   Check the hype:

If you can't validate as per point 1, its possible that the product has just been invented, or the owner of the product has just started to try to release it to the public recently.  NO product that has been out for years should pass point #1.  With time, everything good will be properly validated as described.  Don't be fooled by .... pure hype.

Hype is an attempt by fake or scammy product owners to pass their product as valid by getting people excited about it by using big words and big promises.  This creates an effect where people simply believe its all true and thus are affected by the aforementioned "Placebo Effect".  They believe that it works for them, ergo, it does (in their mind).  If confronted by a double blind study, it would break their enthusiasm some and if reverse engineered and seen that it doesn't work, most would still believe in it.  Its often Hope that creates this illusion in our psyche and many of us will stick to it like there is no tomorrow.

Scam artists use words like Miracle, Proven technology, research says etc..... and use titles like Doctor as well as the number of people that have been helped or served by the product in an attempt to lull people into a sense of security that the product is valid and works well.  I mean, if this Doctor says 100,000 people have tried it and it worked for them, it should be good for me... right?

WRONG !!!

Anyone can get a doctorate from any university.  Its not that simple.  And many "doctors" don't even bother to do that.  This notwithstanding, numbers don't matter thanks to the placebo effect. 

Stay away from shiny words and large promises that this product will make all your problems go away.  Look for reasonable reproducible research by people that know what they are doing and that have no financial incentive in telling you the product is good or bad.  Product users are biased.  Don't fall into that trap!

And for your own sake, avoid the "get in on the ground floor!" comment.  This is to get your money before you figure out too late its a scam, drawing on your excitement and desire/hope for a better future.

3.   If its too good to be true, it probably is:

If all else fails, and you're still unsure, just say that a thousand times in 24 hours so you stop yourself from making a mistake.  Give the product and company some time on ice until there is (1.  Good validation, or 2.  the tone of the promotion is more fact and less hype), then you can check it out.  The real deals will get validated with a bit of time... people like me and actual large companies will validate the whole thing for you, and you can enjoy it.


KESHE PLASMA GENERATORS
Point by point.
1.  This is currently not validated technology.  But since lots of information is out and some equipment is being sold, 3rd party validation will be forthcoming.... unless of course we all got scammed on purchasing the devices....  But in my team's case, we chose to take the risk for now, so that we can share results with you all.  We feel pretty confident that we'll receive something though... we'll see soon enough.

2.  There is some hype about this, but frankly this is not the typical hype.  M. Keshe is spending 90% of his time talking about world peace and how to distribute the technology to the world as easily as possible, for the most part, for free or at soon-to-be-reduced prices (down to about $100 from my reckoning).  The power of the device is reasonable and the reasoning on the impact of free energy in every home is fairly accurate based on my extensive analysis of the world energy consortiums and how things work internationally... yeah, it'll be a huge shit disturbance and yes, it could lead to peace (or at least it could be used as leverage to give it a really good shot).

3.  Its not that far-fetched that we'd figure this out... generating energy in self-contained device could have been imagined years ago, so why not now.  I do have doubts on how Magrav tech can be applicable to Health and curing disease though... THAT sounds quite far-fetched.   But that can be properly tested as per above when the time comes.  Testing and reverse engineering the devices trumps any hype or outlandish claims since we'd have it working in our hands and we can do proper research then to check every other claim out.  My spidey senses tell me that the Health benefits of the tech is hogwash but that the rest (space travel, energy generation, transportation applications etc....) are quite valid and reasonable.

Hope this helps everyone make their minds a bit more about the Keshe plasma generator as well as any other product based offering you may encounter.

Avoid scams, focus your energy on the "good ones".

Peace out !!!!